A deal dies not from a “no” but from silence, a forgotten address and a contact who moved on.

Catalyst finds new clients — and brings back old ones — for CRO, CDMO and CMO teams: it spots the reason to write, drafts the email in the rep’s voice and hands it over for approval.

The deck is written for CROs. A CDMO or CMO? Name your direction on the contact form and a founder replies with what fits it.

Who this is for

A CRO — medicinal chemistry, screening, biology, DMPK, preclinical or clinical services. A CDMO or CMO — development, manufacturing, packaging and supply, with buyers in CMC and supply chain, whose oldest deals still sit in a spreadsheet. Either way, your new business is a few high-value contracts with pharma and biotech, won through people rather than advertising. You own the pipeline. Your mailbox, CRM and LinkedIn stay yours.

42,966

new clinical studies registered in 2025

ClinicalTrials.gov · by first-posted date · counted 13 September 2026

62,804

NIH-funded projects in fiscal year 2025

NIH RePORTER · NIH only, sub-projects excluded · counted 13 September 2026

46

novel drugs approved by the FDA in 2025

FDA Center for Drug Evaluation and Research · Novel Drug Approvals for 2025 · checked 13 September 2026

$69.6–85.4B

research outsourced to CROs in 2025

$197.4–258.9B

development and manufacturing outsourced to CDMOs in 2025

published estimates for 2025: Precedence Research (Feb–Mar 2026), MarketsandMarkets (Apr 2026), Mordor Intelligence (Sep 2026)

What you get

A reason to write today, a draft in your rep’s voice, one tap.

01

The rep decides — the system carries out

A draft waits in the rep’s workspace until a human taps “send” or “skip”; auto mode sends without a tap only where you have switched it on.

02

A reply becomes a deal

What moves forward becomes a deal in your CRM — owner, stage and value.

03

Follow-ups continue without a reminder

Nobody disappears in silence — the next touch is drafted and ready when it is due.

Catalyst finds the pulse in deals that went quiet.

How it works — one loop

Examples are invented — the situations, people, companies and emails.

  1. Signal
  2. Email
  3. Reply
  4. Reactivation
  5. Sprint
  1. 01 · Signal

    A public event points to a company, then a person.

    A grant, a funding round, a clinical milestone — each means new budget or new work. The signal points to the company, the company to the right person.

    Signal → person → email → reply → deal — and back01 / 05

    Yesterday: a grant for a lead-compound program at a biotech

    • public registry entry
    • Dr. Lena Hart, Chief Scientific Officer
    • address verified
  2. 02 · Email

    A draft in the rep’s voice, from approved facts only.

    The card carries the trigger and any warnings. One tap — send, skip, mark bad text, or take the contact. It goes from the rep’s own mailbox.

    Signal → person → email → reply → deal — and back02 / 05

    Congratulations on the grant — DMPK capacity when the program needs it

    • address verified
    • no live conversation at this company
    • not Big Pharma
    • within this week’s sending cap

    One tap

    • send
    • skip
    • bad text
    • take the contact
  3. 03 · Reply

    Every reply is read, classified and given an action.

    “Timing is right — can we talk on Tuesday?” Classified as interested: the rep is alerted, and the reply arrives already drafted in the same thread.

    Signal → person → email → reply → deal — and back03 / 05

    Not every reply is a person

    • out-of-office → the sequence keeps its schedule
    • a hard bounce → the address goes on the do-not-contact list
    • an unclear reply → a person decides, not the model

    Deal in the CRM

    • owner
    • stage
    • value

    no reply — the next email in the sequence, on schedule; sooner with a new signal

  4. 04 · Reactivation

    A deal that went quiet comes back.

    Four months of silence at the discussion stage: the next email picks up where the last call left off, in the same thread — a short sequence, no repeats.

    Signal → person → email → reply → deal — and back04 / 05

    Following our discussion on the DMPK package

    • deal still open in the CRM
    • no reply since the last touch
    • the same thread as before

    The answer

    • “not now — after the review” → a pause with a return date
    • “yes, let’s set the scope” → the deal moves forward
  5. 05 · Sprint

    A conference in two weeks — the warm circle first.

    The rep is travelling to a conference: people already in conversation are written to first, then the cold wave — each email on approval.

    Signal → person → email → reply → deal — and back05 / 05

    In town for the forum — a slot to meet

    • the attendee list matched to your leads
    • the sprint window’s own cap

    After the event

    • meetings → deals in the CRM
    • people return to the usual engines

Catalyst in numbers

All-time totals for one CRO client, shown without its name with its permission — counted from the system’s own logs, updated weekly. Not a forecast.

2,853

public grant and hiring records read

86

kept as a real reason to write — the rest never reached a rep

38

named people found behind those reasons

174

emails drafted in the rep’s voice

201

replies read and given an action

92%

of quiet deals matched back to their contact automatically

Every reply gets an action

The rep only sees what needs a human; pauses, do-not-contact entries and return dates happen on their own.

01

Agreed to a meeting

names a time, books or gives a phone number

alert the rep immediately

02

Interested, nothing specific

“sounds good”, “I’ll check my calendar”

the sequence pauses, the decision is the human’s

03

To a colleague

“talk to X”

contact swap

04

“Not now” or budget frozen

a pause with a date; the lead comes back on its own

05

Decline

“not relevant for us”, “we’re covered”

stop and do-not-contact

06

Question about services or price

straight to the rep

07

Left the company

a search for the successor in the same role

08

Project closed or went elsewhere

the reason for the loss is recorded

What Catalyst never does

Enforced by the system itself — not a policy someone has to remember.

invent a fact

figures and claims about your company come from a single list kept by a human; what is not on it is not written.

invent a history

a first email never “reminds” anyone of a conversation that never happened.

obey a lead’s text

a reply is handed to the model as data, with an instruction not to follow commands in it.

email Big Pharma on its own

a corporation with subsidiaries gets a manual card for the rep, not an automated email.

touch a person twice at once

email, LinkedIn and — for key contacts, on an approved card — SMS take turns, and other people’s deals are never touched.

attach a file

files are never attached to an email to your leads.

write to someone who said no

one do-not-contact list, shared by every engine.

Your team, your data

Your accounts stay yours — the boundary is enforced by the database.

EU region · isolation · full export

hosted in an EU region; isolation enforced by the database itself; a full export at any time, in a standard database format

No footer, no email

the gates require a signature, a title, the company’s postal address and an unsubscribe line

Address check before every email

an address that fails the check gets no email — far fewer bounces reach your domain

56%

of all steps handle failure, not the work

More than half of the system exists for what goes wrong — 56% of all steps handle failure rather than the work itself

measured in September 2026 · how data is handled

Two ways to run it

Subscription pricing is discussed on the first call.

Format A

Your team runs it

Day to day, and the know-how stays with your team; we support the setup and the rules.

Format BRecommended

Turnkey — we run it for you

Our business development manager runs the engines and takes leads to the call — inside your accounts and in your rep’s voice.

The questions a buyer asks first

Short answers about your data; the full terms will go into the data processing agreement each client signs.

01Whose data is it?

Yours. Every lead, email, note and reply belongs to your workspace. You can have a full export at any time in a standard database format — ask us and we will deliver it.

02Can another client see our leads?

The database itself enforces the boundary, not only the app: every record is tied to your workspace, and isolation tests try exactly that — one client reading another’s data.

03Where is the data stored?

Your database is hosted in a European Union region, where the provider stores and primarily processes it. Providers that process your data are listed by category on the subprocessors page; clients receive the named list and advance notice of changes under the data processing agreement.

04Who sends the emails?

Your rep, from their own mailbox, in the same thread. Nothing goes out from a shared Kason address, and each client sends only from its own accounts.

05What happens when we leave?

You take a full export of your data. And when someone leaves your team, their leads are handed over along a documented path — nothing is lost in a chat.

06Someone asked to be erased — then what?

The system recognizes the request on its own and raises an alarm well before the legal deadline. The erasure is completed within the legal deadline; only a minimal record of the refusal is kept, so the address is not written to again.

07Can we pause all outgoing email at once?

Yes — one key pauses Catalyst’s outgoing email within seconds, and sending is capped over a rolling week.

Stop losing deals to silence.

Catalyst finds the right moment to reach out and drafts in your rep’s voice.

Security · how data is handled · subprocessors · privacy